Research & Trials
Research is a vital aspect of the health care industry. Memorial is committed to improving patient care through world-class research institutions and personnel.
Memorial affiliates conduct in-depth research in many areas to help determine the safety and effectiveness of new treatments, medications and devices. Some of our key areas of research are cardiology, oncology, neurosciences, infectious diseases and pulmonary medicine.
The Graduate Medical Education and Research Department partners with Memorial’s Research Oversight Committee and research personnel to protect the rights, welfare, and well-being of human subjects involved in research within the Memorial system.
The Department of Clinical Research has the responsibility of adhering to and abiding by all regulatory requirements including those from the Office of Human Research Protections (OHRP), the Institutional Review Boards of the affiliated institutions (IRBs) and The Joint Commission. The Department of Clinical Research has the responsibility of maintenance for various systems required for providing management reports. Those services include:
- Review all research protocols and required documents in order to support Memorial’s Research Oversight Committee in determining risks and benefits to patients.
- Serve as liaisons for but not limited to Memorial’s Research Oversight Committee, Compliance, Information Security, Information Technology, Legal and On-Boarding/Training departments
Cardiac & Critical Care Services Research Trials
Myocardial Ischemia and Transfusion (MINT)
Includes a randomized, multi-center trial evaluating transfusion strategy for MI patients with hemoglobin levels less than 10g/dL. The study is OPEN for enrollment.
- Sponsor: National Institutes of Health
- Investigator: Paul Mullen, MD
- Site: Memorial
Care Optimization Through Patient and Hospital Engagement Clinical Trial for Heart Failure (CONNECT-HF)
A large-scale, pragmatic, cluster-randomized clinical trial to evaluate the effect of 2 quality improvement initiatives compared with usual care of heart failure (HF) outcomes and HF quality of care metrics at 1 year after discharge for participants hospitalized with acute HF and reduced ejection fraction. The study is CLOSED for enrollment.
- Sponsor: Duke Clinical Research Institute (DCRI)
- Investigator: Paul Mullen, MD
- Site: Memorial
XePOHCAS
A prospective, randomized, multi-center, interventional trial in adult subjects with out-of-hospital cardiac arrest comparing treatment with standard-of-care post-arrest intensive care (which is targeted temperature management [TTM]) to standard-of care post-arrest intensive care (including TTM) plus xenon by inhalation. The study is CLOSED for enrollment.
- Sponsor: NeuroproteXeon, Inc.
- Investigator: Joseph Bosarge, MD
- Site: Memorial
Humanitarian Use Devices (HUD) used in the Cardiac Catheterization Lab – these are devices intended to benefit patients with various, less common (not more than 8,000 in the US per year) conditions.
Forms & Documents
Additional Information
- https://www.fda.gov
- https://www.hhs.gov/ohrp/
- https://www.niaid.nih.gov/research/human-subjects-research-training
- https://www.hhs.gov/ohrp/regulations-and-policy/belmont-report
- https://clinicaltrials.gov
The Memorial Research Team
Gretchen Holmes, PhD
Supervisory Health Scientist
Dept. of Medical Education & Clinical Research
By email at gholmes@mhg.com
By phone at (228) 867-5146
By phone at (228) 990-5685 mobile
By fax at (228) 575-1937
Emily Foret, PhD, MBA
Clinical Research Coordinator
Manager, Clinical Research and Graduate Medical Education
By email eforet@mhg.com
By phone at (228) 867-4998
By phone at (228) 243-2822 mobile